Results 121 to 130 of about 60,858,562 (313)

Capacity Building in Research on Traditional Medicine: Experience of a Workshop Conducted under the Aegis of the Indian Council of Medical Research [PDF]

Journal of Clinical and Diagnostic Research
Training healthcare professionals in research methodology is essential to promote research and innovation. This is particularly relevant in India, where there is a wealth of potential drug candidates from Indian Traditional Medicine (TM) systems that ...
Padmaja Anil Marathe, Sandhya Kaustubh Kamat, Harshad Vijay Kesari, SG Pooja, Nirmala N Rege, Nilima A Kshirsagar   +5 more
doaj   +1 more source

Design as a Critical Research

Libro de Actas - Systems & Design: Beyond Processes and Thinking (IFDP - SD2016), 2016
Historically the imaginary and the hegemonic thinking, in the Western North globe has been marked by the epistemology and capitalists archetypes. Notwithstanding the design as a practice and discipline seem shielded on a simplistic discourse of functional / communicative efficiency, wandering through multiple aestheticism apparently neutral in relation
Calejo, Marta, Magalhães, Graça Maria Alves dos Santos   +1 more
openaire   +4 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Demystifying Theoretical Sampling in Grounded theory Research

Grounded Theory Review: An International Journal, 2009
Theoretical sampling is a central tenet of classic grounded theory and is essential to the development and refinement of a theory that is ‘grounded’ in data.
Jenna Breckenridge, Derek Jones
doaj  

Multiple intelligibility in constructive design research: The case of empathic design [PDF]

, 2020
This paper studies intelligibility in constructive design research, in which the main instrument of knowledge creation is design. Constructive design research is situated between design practice and research, meaning it has to build on practices that ...
Whalen, Jack, Koskinen, Ilpo, Lee, Jung Joo   +2 more
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Research-Through-Design: Exploring a design-based research paradigm through its ontology, epistemology, and methodolog

, 2018
Design research has risen in prominence over the past 20 years resulting in substantial discussion regarding it’s ontological and epistemological foundation, but there has been limited progression towards consolidation of the disparate views into a ...
Isley, C. Grey, Rider, Traci, C. Grey Isley, Traci Rider   +3 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Happy moments: A well-being driven design of a Car2Go

, 2016
User well‐being is increasingly addressed in design and design research. Previous work has proposed a design for well-¬‐being framework that includes three main ingredients: pleasure, personal significance, and virtue. While useful for analysing the well-
Duste, Tessa, van Grondelle, Elmer, Duste, T. (author), Tessa Duste, Elmer van Grondelle, Pieter Desmet, Desmet, Pieter, Desmet, P.M.A. (author), van Grondelle, E.D. (author)   +8 more
core   +1 more source