Results 101 to 110 of about 2,632,433 (266)
Design and quality criteria for archetype analysis
Ecology and Society, 2019 A key challenge in addressing the global degradation of natural resources and the environment is to effectively transfer successful strategies across heterogeneous contexts.
Klaus Eisenack +8 more
doaj +1 more source
Happy moments: A well-being driven design of a Car2Go
, 2016 User well‐being is increasingly addressed in design and design research. Previous work has proposed a design for well-¬‐being framework that includes three main ingredients: pleasure, personal significance, and virtue. While useful for analysing the well-
Duste, Tessa +8 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Striking a Balance between Program Requirements and GT Principles
Grounded Theory Review: An International Journal, 2009 Glaser’s term “compromised GT proposal” (2001, p.114) refers to the type of Grounded Theory (GT) proposal that is written in order to conform to the requirements of a standardized qualitative research proposal.
Sherry L. Xie
doaj
Proximity in Design Research explores four constituents of design: people, processes, products and philosophy, and their potential to bridge contemporary gaps through multilevel synergies.
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Demystifying Theoretical Sampling in Grounded theory Research
Grounded Theory Review: An International Journal, 2009 Theoretical sampling is a central tenet of classic grounded theory and is essential to the development and refinement of a theory that is ‘grounded’ in data.
Jenna Breckenridge, Derek Jones
doaj
Efficacy and Mechanism EvaluationBackground Nutrition is essential for preterm brain development. Optimal nutrition is dependent upon gastrointestinal health. Primary objective To form a multiprofessional collaboration to design the world’s first neonatal precision-medicine platform ...
Neena Modi +17 more
doaj +1 more source
, 2018 Design research has risen in prominence over the past 20 years resulting in substantial discussion regarding it’s ontological and epistemological foundation, but there has been limited progression towards consolidation of the disparate views into a ...
Isley, C. Grey +3 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source