Results 91 to 100 of about 60,858,562 (313)
Strange bedfellows: Design research and behavioral design
Behavioral design—the application of behavioral economics principles to real-world challenges—has achieved success across a variety of domains, yet its scale and effectiveness has been limited by its narrow focus on behavioral change to frame problems ...
Ruth Schmidt, Schmidt, Ruth
core +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Research designs require flexibility, and adjustments made to the designs do not always have to lead exclusively to disadvantages. In this research note, we would like to share our reflections on the impact of COVID-19 on the conduct of qualitative ...
Maria Gruber +3 more
doaj +1 more source
Overview of research designs [PDF]
The fourth paper in the research series looks at the difficulties in establishing truth for the researcher and provides an overview of research design.
openaire +2 more sources
How Maps Shape Information in Design Research: A Study of Five Method Collections [PDF]
Maps have a rich history in design and design research. However, to date, their use and application have not been systematically studied. This paper proposes a model that classifies maps into four main types depending on how they help designers to ...
Koskinen, I +3 more
core +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Physiological measurements of drawing and forming activities [PDF]
The embodiment of tools and experiential knowledge of materials gained over time lies at the heart of both design and craft practices. However, empirical studies combining the study of mind and body in relation to design and craft practice is in its ...
Groth, Camilla +11 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source

