Results 91 to 100 of about 2,632,433 (266)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
International Brazilian Journal of Urology, 2014 Purpose Scientific research originating from Brazil appears to be rising in several medical fields. Research results are often presented at scientific meetings before publication in peer-reviewed journals.
Marco A. Arap +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Analysis of Information in the Academic Management of the UNED, Required in the Self-Assessment Processes and the Relation Between Research and Design of the Investigation [PDF]
Journal of Systemics, Cybernetics and Informatics, 2019 One of the institutional concerns of the Distance State University (UNED) to obtain appropriate information to sustain continuous improvements in the Diplomaed and Bachelor's degree and postgraduate program's to reach academic excellence.
Ariana Acón-Matamoros +1 more
doaj
Ecology and Society, 2019 Ecosystem services inherently involve people, whose values help define the benefits of nature's services. It is thus important for researchers to involve stakeholders in ecosystem services research.
Heather A. Schoonover +7 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Legitimization of Improvement Science in Academe [PDF]
Journal of Systemics, Cybernetics and Informatics, 2019 This article examines improvement science (Bryk, 2009) against the backdrop of traditional academic research methods. Improvement science is perhaps most closely aligned with design-based implementation research, and is typically applied to networked ...
Casey D. Cobb, Patricia Virella
doaj
Libro de Actas - Systems & Design: Beyond Processes and Thinking (IFDP - SD2016), 2016 Historically the imaginary and the hegemonic thinking, in the Western North globe has been marked by the epistemology and capitalists archetypes. Notwithstanding the design as a practice and discipline seem shielded on a simplistic discourse of functional / communicative efficiency, wandering through multiple aestheticism apparently neutral in relation
Calejo, Marta +1 more
openaire +5 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Seminars in Proactive Artificial Intelligence for Cybersecurity (SPAIC): Consulting and Research [PDF]
Journal of Systemics, Cybernetics and Informatics, 2019 The authors have designed a platform for research and consulting through a high-level collaborative seminar series to promote networking in proactive artificial intelligence (AI) for cybersecurity (SPAIC).
Ehsan Sheybani, Giti Javidi
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