Results 91 to 100 of about 60,858,562 (313)

Strange bedfellows: Design research and behavioral design

open access: yes, 2020
Behavioral design—the application of behavioral economics principles to real-world challenges—has achieved success across a variety of domains, yet its scale and effectiveness has been limited by its narrow focus on behavioral change to frame problems ...
Ruth Schmidt, Schmidt, Ruth
core   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Qualitative Interviews with Irregular Migrants in Times of COVID-19: Recourse to Remote Interview Techniques as a Possible Methodological Adjustment

open access: yesForum: Qualitative Social Research, 2020
Research designs require flexibility, and adjustments made to the designs do not always have to lead exclusively to disadvantages. In this research note, we would like to share our reflections on the impact of COVID-19 on the conduct of qualitative ...
Maria Gruber   +3 more
doaj   +1 more source

Overview of research designs [PDF]

open access: yesEmergency Medicine Journal, 2002
The fourth paper in the research series looks at the difficulties in establishing truth for the researcher and provides an overview of research design.
openaire   +2 more sources

How Maps Shape Information in Design Research: A Study of Five Method Collections [PDF]

open access: yes
Maps have a rich history in design and design research. However, to date, their use and application have not been systematically studied. This paper proposes a model that classifies maps into four main types depending on how they help designers to ...
Koskinen, I   +3 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Physiological measurements of drawing and forming activities [PDF]

open access: yes, 2016
The embodiment of tools and experiential knowledge of materials gained over time lies at the heart of both design and craft practices. However, empirical studies combining the study of mind and body in relation to design and craft practice is in its ...
Groth, Camilla   +11 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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