Results 71 to 80 of about 2,632,433 (266)
Research Design Considerations [PDF]
Journal of Graduate Medical Education, 2016 ‘‘I’d really like to do a survey’’ or ‘‘Let’s conduct some interviews’’ might sound like reasonable starting points for a research project. However, it is crucial that researchers examine their philosophical assumptions and those underpinning their research questions before selecting data collection methods. Philosophical assumptions relate to ontology,
Sarah, Wright +4 more
openaire +2 more sources
Design Research and Design Participation
, 2016 This paper brings together some key research issues in design participation: Is it possible to develop a computer-based architectural design application which can be used by completely untutored lay participants in a meaningful design process?
Robert Aish, Aish, Robert
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi +6 more
wiley +1 more source
Strange bedfellows: Design research and behavioral design
, 2020 Behavioral design—the application of behavioral economics principles to real-world challenges—has achieved success across a variety of domains, yet its scale and effectiveness has been limited by its narrow focus on behavioral change to frame problems ...
Ruth Schmidt, Schmidt, Ruth
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Revista Brasileira de Geriatria e GerontologiaResumo Introdução: estudos sobre o idoso que vive na Região Norte do Brasil ainda são incipientes e necessários para subsidiar programas de saúde pública.
Euler Esteves Ribeiro +6 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
, 2010 This paper addresses the role of the designer as actor/agency working within and across flows of knowledge, perception and information for filtering, negotiating and mediating design decision making.
Shumack, Kaye (R8571)
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source