Results 111 to 120 of about 60,858,562 (313)

The Legitimization of Improvement Science in Academe [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2019
This article examines improvement science (Bryk, 2009) against the backdrop of traditional academic research methods. Improvement science is perhaps most closely aligned with design-based implementation research, and is typically applied to networked ...
Casey D. Cobb, Patricia Virella
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Seminars in Proactive Artificial Intelligence for Cybersecurity (SPAIC): Consulting and Research [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2019
The authors have designed a platform for research and consulting through a high-level collaborative seminar series to promote networking in proactive artificial intelligence (AI) for cybersecurity (SPAIC).
Ehsan Sheybani, Giti Javidi
doaj  

Design and quality criteria for archetype analysis

open access: yesEcology and Society, 2019
A key challenge in addressing the global degradation of natural resources and the environment is to effectively transfer successful strategies across heterogeneous contexts.
Klaus Eisenack   +8 more
doaj   +1 more source

Proximity in Design Research

open access: yes
Proximity in Design Research explores four constituents of design: people, processes, products and philosophy, and their potential to bridge contemporary gaps through multilevel synergies.

core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

DIFFICULT FORMS: Critical practices of design and research [PDF]

open access: yes, 2009
As a kind of ‘criticism from within’, conceptual and critical design inquire into what design is about – how the market operates, what is considered ‘good design’, and how the design and development of technology typically works.
Mazé, Ramia, Redström, Johan
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Striking a Balance between Program Requirements and GT Principles

open access: yesGrounded Theory Review: An International Journal, 2009
Glaser’s term “compromised GT proposal” (2001, p.114) refers to the type of Grounded Theory (GT) proposal that is written in order to conform to the requirements of a standardized qualitative research proposal.
Sherry L. Xie
doaj  

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