Results 171 to 180 of about 14,201,106 (332)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Adjustable prosthetic sockets: a systematic review of industrial and research design characteristics and their justifications. [PDF]

open access: yesJ Neuroeng Rehabil, 2023
Baldock M   +10 more
europepmc   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Editor’s Newsletter

open access: yesAustralasian Orthodontic Journal, 1987
doaj   +1 more source

A cost-effective mesocosm framework for reptile research: Design, validation, and practical insights. [PDF]

open access: yesPLoS One
Simbula G   +11 more
europepmc   +1 more source

Redox Profile of Skeletal Muscles: Implications for Research Design and Interpretation. [PDF]

open access: yesAntioxidants (Basel), 2023
Vasileiadou O   +6 more
europepmc   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

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