Results 181 to 190 of about 7,571,378 (315)

Hydrogel Microspheres as Versatile Platforms for Biomedical Research: Design, Properties, and Applications. [PDF]

MedComm (2020)
Yang M, Shi Y, Wang F, Zhang X, Shao J, Yang F, Sun H, Zhang C, Zhou Z, Huang J, Lv P, Yung PS, Cheng J, Huang HJ, Wang JQ.   +14 more
europepmc   +1 more source

Adjustable prosthetic sockets: a systematic review of industrial and research design characteristics and their justifications. [PDF]

J Neuroeng Rehabil, 2023
Baldock M, Pickard N, Prince M, Kirkwood S, Chadwell A, Howard D, Dickinson A, Kenney L, Gill N, Curtin S, Curtin S.   +10 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The longitudinal qualitative research design in nursing, health, and social care research: philosophy, methodology, and methods. [PDF]

BMC Med Res Methodol
Bayuo J, Nyande FK, Awunyo W, Akpalu E.
europepmc   +1 more source

Redox Profile of Skeletal Muscles: Implications for Research Design and Interpretation. [PDF]

Antioxidants (Basel), 2023
Vasileiadou O, Nastos GG, Chatzinikolaou PN, Papoutsis D, Vrampa DI, Methenitis S, Margaritelis NV.   +6 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Monitoring technology for pest-plant interactions : The need for transdisciplinary research design. [PDF]

EMBO Rep
Cavazzoni E, Leonelli S, Giannetti D, Patelli N, Vaccari G, Maistrello L, Pinotti MC.   +6 more
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The role of mindfulness training supported by virtual reality in the nonpharmacological treatment of schizophrenia-research design. [PDF]

Ann Gen Psychiatry
Cechnicki A, Chrobak A, Plencler I, Stankiewicz P, Kalisz A, Błądziński P, Kruk D, Radoń S, Szewczyk B, Faron-Górecka A, Korostyński M, Siwek M.   +11 more
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source