Results 171 to 180 of about 77,036,499 (314)

Research Design: The explorative potential of research-planning processes in visual and material culture

On_Culture, 2016
Alesya Krit
doaj  

The Relationship Between Nurses' Approaches to Ethical Issues and Their Attitudes Towards Principles of Ethics: A Descriptive, Correlational Research Design. [PDF]

J Eval Clin Pract
Sahiner P.
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Research Design Processes in Serious Games for Adolescent Mental Health: Systematic Review. [PDF]

JMIR Serious Games
Rooij de ST, Kuipers DA, Prins JT, Pierie JPEN.   +3 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Perception of physiotherapy researchers about patient and public involvement in health research design and planning in Nigeria. [PDF]

BMC Health Serv Res
Fawole HO, Osuji PO, Idowu OA, Obiekwe SJ, Kolawole FO, Fatai KE, Okafor AC, Aku-Dania GA, Bolu CD, Adeniji T, Akinrolie O.   +10 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Addressing anti-black racism - advancing equity and empowering black registered practical nurses: A multiple method research design. [PDF]

Int J Nurs Stud Adv
Prendergast N, Boakye P, Borges A, Ahmed E, Calver J, Oliver M, Reid K.   +6 more
europepmc   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Does Increasing Sample Size Inevitably Lead to Statistical Significance? Insights From a Monte Carlo Simulation Study for Medical Research Design. [PDF]

J Eval Clin Pract
Li M, Yang S, Wang Y, Xin Z, Sun Y, Li Y, Gao L, Xu Z, Bi J.   +8 more
europepmc   +1 more source