Results 181 to 190 of about 40,886,999 (373)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

A cost-effective mesocosm framework for reptile research: Design, validation, and practical insights. [PDF]

PLoS One
Simbula G, Barroso FM, Saçdanaku E, Ene G, Fănaru G, Sreelatha LB, Vizireanu MG, Roumelioti M, Boskovits NM, Vlad SE, Aguilar P, Carretero MA.   +11 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Guest editorial: From research design to the waiting room. [PDF]

Qual Res Med Healthc
Hopeck P.
europepmc   +1 more source

Design and experimental research of air-assisted nozzle for pesticide application in orchard

Mingxiong Ou, Jiayao Zhang, Wen-Tao Du, Minmin Wu, Tianyu Gao, Weidong Jia, Xiang Dong, Tierui Zhang, Suming Ding   +8 more
openalex   +1 more source

The Design and Research of an Oral Examination Management System Based on Node.js

, 2018
Wei-na ZHU, Yansong Cui, Dan-zhi WANG
openalex   +2 more sources

Using Thematic Analysis to Facilitate Meaning‐Making in Practice‐Led Art and Design Research [PDF]

, 2018
Fabia Ling‐Yuan Lin
openalex   +1 more source

Qualitative Research Design: An Interactive Approach

, 1998
M. Pitman
semanticscholar   +1 more source

DeResA: a DEsign RESearch Approach [PDF]

, 2006
Slettenhaar, H.K., Vries, S.A. de
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source