Results 51 to 60 of about 12,942,505 (384)
Blockchain is predicted to disrupt industries, economies, and societies. The properties of distributed ledgers allow the creation of immutable data structures that facilitate shared access in real time and enable a plethora of innovative applications ...
Horst Treiblmaier
doaj +1 more source
The development of a good research design permits us to obtain the best research data possible. From the experimental question to the research hypothesis and data collection variables, we can begin to consider the optimal research design. Details pertaining to the selection of the research design are considered within and very much in relation with the
openaire +2 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Background: In response to the COVID-19 pandemic, member countries of the Organisation for Economic Co-operation and Development (OECD) rapidly published guidance regarding the conduct of clinical research.
Renu Bhutkar+3 more
doaj +1 more source
Design research and visual analysis [PDF]
Design research has been built on the method and contextual paradigms that have been the traditions of a range of other research areas. This situation creates distinct issues and challenges for the researcher and the research community.
Buchler, D.
core
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr+4 more
wiley +1 more source
[english] Objectives: Medical education is gaining in significance internationally. A growing interest in the field has been observed in German-speaking countries (Austria, Germany, Switzerland) since the early 2000s.
Raes, Patricia+3 more
doaj +1 more source
Adapting an Educational Software Internationally: Cultural and Linguistical Adaptation
This study protocol proposes an adaptation of the participatory and iterative process framework for language adaptation (PIPFLA). The adapted model follows five dimensions for a cross-cultural equivalence model: semantic, content, technical, criterion ...
Samia Valeria Ozorio Dutra+2 more
doaj +1 more source
Design Science Research Process: A Model for Producing and Presenting Information Systems Research [PDF]
The authors design and demonstrate a process for carrying out design science (DS) research in information systems and demonstrate use of the process to conduct research in two case studies. Several IS researchers have pioneered the acceptance of DS research in IS, but in the last 15 years little DS research has been done within the discipline. The lack
arxiv
Reasons, Challenges and Some Tools for Doing Reproducible Research in Transportation Research [PDF]
This paper introduces reproducible research, and explains its importance, benefits and challenges. Some important tools for conducting reproducible research in Transportation Research are also introduced. Moreover, the source code for generating this paper has been designed in a way so that it can be used as a template for researchers to write their ...
arxiv