Results 51 to 60 of about 4,766,757 (295)
Architectural Research Quarterly, 2017 Early issues of arq in the mid-1990s were preoccupied with the possibilities for researching architecture through design: how design research might be constituted and communicated, and – practically for architecture schools at that time – how design might be counted as research in the newly-introduced metrics used to judge research quality in UK ...
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Research Design Considerations [PDF]
Journal of Graduate Medical Education, 2016 ‘‘I’d really like to do a survey’’ or ‘‘Let’s conduct some interviews’’ might sound like reasonable starting points for a research project. However, it is crucial that researchers examine their philosophical assumptions and those underpinning their research questions before selecting data collection methods. Philosophical assumptions relate to ontology,
Laura Nimmon +4 more
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Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Discussion: “Modern Steam Passenger Locomotives—Research and Design” (Kiefer, P. W., 1942, Trans. ASME, 64, pp. 1–13) [PDF]
, 1942 J. E. Partington
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FEBS Letters, EarlyView.Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley +1 more source
A Systemic/Cybernetic Notion of Design [PDF]
Journal of Systemics, Cybernetics and Informatics, 2019 The purpose of writing this article is 1) to describe the notion1 of "design" in order to show that there is almost no thought-based activity that does not, explicitly or implicitly, contains designing activities, including academic and scientific ones ...
Nagib Callaos
doaj
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Placing fandom, studying fans: Modified acafandom in practice
Transformative Works and Cultures, 2020 For nearly three decades, the field of fan studies has helped to shift the conversation on fandom from a study of pathological individuals to exploring how groups make use of and transform the contemporary media landscape. Fandom itself is also changing.
Abby Waysdorf
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FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source