Results 51 to 60 of about 40,886,999 (373)
Deconstructing Design Research [PDF]
The Design Journal, 2019 This paper presents a novel conceptual framework for assessing design research projects. Present-day design research is typified by projects, which traverse disciplinary, methodological, and conceptual boundaries that often have wide-ranging social, cultural, and economic impact to industry, government bodies, and the wider public.
Rodgers, Paul A. +2 more
openaire +4 more sources
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
Revista Brasileira de Geriatria e GerontologiaResumo Introdução: estudos sobre o idoso que vive na Região Norte do Brasil ainda são incipientes e necessários para subsidiar programas de saúde pública.
Euler Esteves Ribeiro +6 more
doaj +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Health Technology Assessment, 2021 Background: Measurement can affect the people being measured; for example, asking people to complete a questionnaire can result in changes in behaviour (the ‘question–behaviour effect’).
David P French +8 more
doaj +1 more source
, 2018 This study is aimed at to contribute a detailed systematic review on research paradigms, sampling and instrument development issues in the field of business research.
S. Rahi
semanticscholar +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
YourMOOC4all: a MOOCs inclusive design and useful feedback research project [PDF]
, 2018 User feedback can be of great value for the development of guidelines to design MOOC platforms, courses, and open educational resources. Considering other learners’ experiences may benefit the development of course recommender systems that consider not ...
Iniesto, Francisco, Rodrigo, Covadonga
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Keynote address: Design Research and Academic Disciplines [PDF]
, 2009 This article, published in Design Research Quarterly (3:4) October 2008, is based on the keynote address given by Prof Alan Blackwell at the DRS conference in 2008. Design Research Quarterly.
Blackwell, Alan
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