Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
Current status and factors influencing research ethics knowledge and attitudes among pediatricians: a cross-sectional survey. [PDF]
Zheng B, Zhang N, Qin H, Zhu L.
europepmc +1 more source
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Could lessons from medical research ethics inform better conversations and governance for climate engineering research. [PDF]
Fitzgerald SD +3 more
europepmc +1 more source
Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle +4 more
wiley +1 more source
Topography of Human Subjects Research Ethics in Uzbekistan: Analysis Using the Emanuel Benchmarks. [PDF]
Aniyozova D, Munir K.
europepmc +1 more source
Disciplinary Research Ethics Cultures in Disaster Settings: Understandings from Researchers After 3.11 in Japan. [PDF]
Abeysinghe S +5 more
europepmc +1 more source
The role of research ethics committees in addressing optimism in sample size calculations: a meta-epidemiological study. [PDF]
Jansen MS, Groenwold RHH, Dekkers OM.
europepmc +1 more source

