Results 51 to 60 of about 5,021,475 (359)
Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack +12 more
wiley +1 more source
Patient apprehensions about the use of artificial intelligence in healthcare
While there is significant enthusiasm in the medical community about the use of artificial intelligence (AI) technologies in healthcare, few research studies have sought to assess patient perspectives on these technologies.
Jordan P. Richardson +6 more
doaj +1 more source
The 'problem' of ethics in contemporary anthropological research [PDF]
Why is it that ‘ethics’ is seen as a problem in anthropology? This paper seeks to explore this question by looking at (a) historical shifts in the relation between ethnographers and their subjects/informants and (b) anthropological practice.
Campbell, John
core +1 more source
ABSTRACT Background Psychological safety (PS) is essential for teamwork, communication, and patient safety in complex healthcare environments. In pediatric oncology, interprofessional collaboration occurs under high emotional and organizational demands. Low PS may increase stress, burnout, and adverse events.
Alexandros Rahn +4 more
wiley +1 more source
Importance of consent in the research
Research involving human participants needs to be scientifically valid and should be conducted according to accepted ethical standards. Research ethics provides guidelines for responsible conduct of research on human participants.
Naresh Manandhar, Dr +1 more
doaj +1 more source
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker +7 more
wiley +1 more source
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu +20 more
wiley +1 more source
Research Ethics Committees [PDF]
Trials and Tribulations by Saul Miller1 takes the National Research Ethics Service to task for the closure of the Northumberland Research Ethics Committee (REC), but there are compelling reasons behind this decision. The Northumberland closure is part …
openaire +2 more sources
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li +9 more
wiley +1 more source
Gendered Violence and the Ethics of Social Science Research [PDF]
The issue of ethical conduct in research settings is important and complex. As tenure-track researchers who study gendered violence, we found Clark and Walker’s discussion provocative, thoughtful, and interesting.
Hlavka, Heather R, Mulla, Sameena A.
core +1 more source

