Results 71 to 80 of about 53,502,383 (247)

The new International Health Regulations and the federalism dilemma. [PDF]

open access: yesPLoS Medicine, 2006
Kumanan Wilson   +3 more
doaj   +1 more source

Observer l’éthique en train de se faire pour une approche pragmatique des commissions d’éthique de la recherche

open access: yesRevue d'anthropologie des connaissances, 2019
Research ethics commissions (REC) concentrate a large part of the debates on research ethics. However, few ethnographic inquires have been carried out to investigate their work.
Solène Gouilhers, Loïc Riom
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Stop centring Western academic ethics: deidentification in social science research [PDF]

open access: yes, 2018
This blog will provide a discussion of issues present in deidentifying marginalised research participants, or research participants who request to be identified, in the publication of qualitative research. As my research is mixed-method (quantitative and
Denejkina, Anna (R19494), Denejkina, A
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

The ESRC's 2010 Framework for Research Ethics: Fit for Research Purpose? [PDF]

open access: yes
The ESRC\'s (2010) Framework for Research Ethics extends the remit of its 2005 research ethics framework in three significant ways: the system is to be fully mandatory and it will no longer possible to make the case that no out of the ordinary ethical ...
Sue Wise, Liz Stanley
core  

How Should I Care: Research Ethics and Its Tensions in Participatory Action Research

open access: yesDutch Journal of Applied Linguistics
In Shepperd and Dalderop (forthcoming)’s viewpoint Why should I care? Research ethics in the field of adult L2 Literacy, the authors make three important assertions regarding research ethics with so called vulnerable participants.
Amber Bartlett
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy