Results 81 to 90 of about 5,085,695 (304)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
The new International Health Regulations and the federalism dilemma. [PDF]
PLoS Medicine, 2006 Kumanan Wilson +3 more
doaj +1 more source
How Should I Care: Research Ethics and Its Tensions in Participatory Action Research
Dutch Journal of Applied LinguisticsIn Shepperd and Dalderop (forthcoming)’s viewpoint Why should I care? Research ethics in the field of adult L2 Literacy, the authors make three important assertions regarding research ethics with so called vulnerable participants.
Amber Bartlett
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Ethical approval in developing countries is not optional [PDF]
, 2012 When conducting health and medical research it is not only important to do the research ethically, but also to apply for prior ethical approval from the relevant authorities.
Simkhada, Padam, van Teijlingen, Edwin
core +1 more source
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Research Ethics and Fieldwork at New Consumption Communities [PDF]
, 2005 It is hard to deny that marketing practice has changed considerably during recent years. This is reflected in its increased focus on customisation, coproduction and interactive marketing, much of which has been enabled by new information technologies ...
Bekin, C
core