Results 91 to 100 of about 53,262,825 (284)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Hard to reach? Methodological challenges researching vulnerable, gang‐involved, young people

open access: yesHealth Expectations
Introduction Research with young people (YP) is ethically challenging and bound in a complex maze of issues relating to power, voice and representation.
Rhiannon Barker   +2 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

2013 CD#32.1 - Committee on Professional Ethics Report

open access: yes, 2013
The Committee on Professional Ethics report to Council for the 2013 Annual ...
Committee on Professional Ethics
core  

ETHICS COMMITTEES AND INTERNATIONAL COLLABORATIVE RESEARCH IN IRAN AND JAPAN (2002-2003)

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2006
Introduction: The internationally sponsored researches give rise to many important ethical challenges worldwide. Some evidences represent that ethical and scientific standards do not observe in these researches.
B Larijani,   +4 more
doaj  

Research on the Path of the Working Mechanism of Legal Members in Hospital Ethics Review Committees

open access: yesYixue yu zhexue
With the increasing complex ethical review issues brought by the application of cutting-edge technologies such as artificial intelligence medical and gene editing, the role definition and responsibility evolution legal committee of medical ethics ...
Shiyue YE, Mei HUANG, Mingxia WANG
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

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