Results 51 to 60 of about 53,262,825 (284)
Doing the right thing! A model for building a successful hospital-based ethics committee in Nunavut [PDF]
International Journal of Circumpolar Health, 2013 Background. There exists a need throughout the North to increase capacity to address issues of health ethics and for community members to better understand and share their perspectives on this topic.
Madeleine Cole, Gwen Healey
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Challenges associated with ethics review of educational research at a South African university
Acta Academica, 2011 This article analyses the decisions and feedback from reviewers of a decentralised ethics committee to applicants in a two-year period. Results indicate that the review of research protocols by an ethics committee are complicated by challenges related ...
Salome Human-Vogel, Sonja Coetzee
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BMC Medical EthicsThe EU Clinical Trials Regulation (CTR) was introduced to harmonize clinical trial evaluations across Member States while upholding participant protection and ethical integrity.
Audrey Van Scharen +2 more
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Gazi Medical JournalObjective: The process of conducting medical research on human subjects is secured by a number of regulations from its planning phase through its publication as an original article.
Canan Uluoğlu +2 more
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
University Research Cyberinfrastructure Committee Interim Report [PDF]
, 2006 report"Campus cyberinfrastructure is not just about technology." Beyond access to technology, Cyberinfrastructure (CI) defines a new information technology paradigm that includes people and their expertise, enabling technologies, software and tools ...
University Research Cyberinfrastructure Committee
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BMC NursingBackground Oncology nurses have a vital role in providing care for individuals with cancer. Ethical dilemmas arise for oncology nurses caring for these patients.
Akbar Zare-Kaseb +3 more
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source