Results 31 to 40 of about 200,706 (288)

Experiência do comitê de ética em pesquisa de uma universidade pública de Minas Gerais, Brasil

Revista Bioética
O artigo relata experiência do Comitê de Ética em Pesquisa da Universidade Estadual de Montes Claros, MG, Brasil, no período entre 2000 e 2009, com base em pesquisa documental, na modalidade estudo de caso, com nível de significância p < 0,05.
Patrícia Alves Paiva, Simone de Melo Costa, Orlene Veloso Dias, Vânia Silva Vilas Bôas Vieira Lopes, Dardânia Glayce Barbosa Souto, Daniele Lopes da Silva   +5 more
doaj   +1 more source

Identification of ethics committees based on authors’ disclosures: cross-sectional study of articles published in the European Journal of Anaesthesiology and a survey of ethics committees

BMC Medical Ethics, 2018
Background Since 2010, the European Journal of Anaesthesiology has required the reporting of five items concerning ethical approval in articles describing human research: ethics committee’s name and address, chairperson’s name, study’s protocol number ...
Davide Zoccatelli, Martin R. Tramèr, Nadia Elia   +2 more
doaj   +1 more source

National Human Research Ethics: A Preliminary Comparative Case Study of Germany, Great Britain, Romania, and Sweden

, 2015
Although international research is increasing in volume and importance, there remains a dearth of knowledge on similarities and differences in “national human research ethics” (NHREs), that is, national ethical guidelines (NEGs), Institutional Review ...
Berman, Anne H.,, Berman, AH, Jones, Adele D., Urban, Mirjam, Schiratzki, J, Raikes, B, Schiratzki, Johanna, Foca, L, Gallagher, B, Gallagher, Bernard, Gallagher, Bernard,, Jones, Adele D.,, Ullman, Sara, Urban, Mirjam,, Foca, Liliana,, Urban, M, Raikes, Ben, Foca, Liliana, Bieganski, Justyna, Berman, Anne H., Jones, AD, Bieganski, J, Raikes, Ben,, Ullman, S, Jones, Adele, Ullman, Sara,, Bieganski, Justyna,, Ullman, Sarah, Schiratzki, Johanna,   +28 more
core   +1 more source

Evolution of ethics in clinical research and ethics committee

Indian Journal of Dermatology, 2017
Ethics are the moral values of human behavior and the principles which govern these values. The situation becomes challenging for a doctor when he assumes the role of researcher. The doctor-researcher has to serve both the roles and at times the zeal of an investigator has the potential to cloud the morality of the physician inside.
Nilay Kanti Das, Amrita Sil
openaire   +3 more sources

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Rethinking research ethics committees in low- and medium-income countries

Research Ethics Review, 2018
Key historical landmark research malpractice scandals that shocked the international community (Nazi doctors’ experiments, Tuskegee study, Jewish chronic disease experiments, Krugman’s Willowbrook hepatitis study) were the origin of the institution of ...
Luchuo Engelbert Bain, Ikenna Desmond Ebuenyi, Nkoke Clovis Ekukwe, Paschal Kum Awah   +3 more
doaj   +1 more source

Redundant trials can be prevented, if the EU clinical trial regulation is applied duly

BMC Medical Ethics, 2020
The problem of wasteful clinical trials has been debated relentlessly in the medical community. To a significant extent, it is attributed to redundant trials – studies that are carried out to address questions, which can be answered satisfactorily on the
Daria Kim, Joerg Hasford
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Is it time to abandon institutional research ethics committees?

, 2002
Research on human beings has significantly increased in ethical and scientific complexity. Ethics review is at a fork in the road. Either we significantly increase the resources we provide to support institutional research ethics committees.
Savulescu, J., Savulescu, Julian
core   +1 more source

Supporting Survivor‐Centered Care Through Digital Health Integration

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Survivors of childhood cancer face barriers to receiving guideline‐based, long‐term follow‐up care. Two digital tools, Passport for Care (PFC) and Cancer SurvivorLink (SurvivorLink), address complementary gaps by enabling tailored survivorship care plan (SCP) generation, updating, storage, and sharing.
Jordan G. Marchak, Rebecca Williamson‐Lewis, Michael O'Connor, Michael Palgon, Yu‐Ra Kim, Michael Schuckenbrock, Paula Edwards, Abraham Mendoza, Anthony Adams, Brian Arriaga‐Solis, Justin Parker, Harry Tinoco‐Giraldo, Jason King, C. Michael Fordis, Karen E. Effinger, Maria Monica Gramatges   +15 more
wiley   +1 more source