Results 71 to 80 of about 57,215,976 (259)

The CGIAR at 31 : An Independent Meta-Evaluation of the Consultative Group on International Agricultural Research, Revised Edition [PDF]

open access: yes, 2004
The original mission of the CGIAR was a strategic, science-based focus on increasing "the pile of rice on the plates of food-short consumers," as characterized by a former chairman. It was to use the best
Operations Evaluation Department
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Chinese expert consensus on the diagnosis and treatment of leptomeningeal metastasis from breast cancer

open access: yesZhongguo aizheng zazhi
Leptomeningeal metastasis from breast cancer is one of the severe complications of advanced breast cancer, characterized by complex and variable clinical manifestations, rapid disease progression, and an extremely poor prognosis.
Clinical Cancer Research Evaluation Committee of Chinese Medical Education Association   +1 more
doaj  

MANAGING CHANGE IN ACADEMIC LIBRARY: THE CASE OF VILNIUS UNIVERSITY LIBRARY

open access: yesKnjižnica, 2013
Purpose: The main objective of this article is to ascertain some most significant fields of the academic library activities, which have (or could have) an impact on strengthening the library’s role as a partner in academic community, as well as to ...
Marija Prokopčik, Irena Krivienė
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Can informetrics shape biomedical research? A case study of the HIV/AIDS research in sub-Saharan Africa

open access: yesInkanyiso, 2014
Biomedical research is burgeoning as new dangerous diseases and healing methods emerge. Informetrics defined as methods or a research field that uses mathematical and statistical techniques and/or models to examine patterns that show up not only in ...
Omwoyo B. Onyancha
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Research, demonstration, and evaluation studies.

open access: yes
Mode of access: Internet.Continued by: Research, demonstration, and evaluation studies, issued by: United States. Administration for Children, Youth, and Families.
United States. Office of Child Development. Research and Evaluation Division.
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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