Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Areas of research focus and trends in the research on the application of AIGC in healthcare. [PDF]
J Health Popul NutrWang C +6 more
europepmc +1 more source
Exploring changes in depression and radiology-related publications research focus: A bibliometrics and content analysis based on natural language processing. [PDF]
Front Psychiatry, 2022 Wang K, Tan F, Zhu Z, Kong L.
europepmc +1 more source
The methodology of focus groups: the importance of interaction between research participants
, 1994 J. Kitzinger
semanticscholar +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Research focus and trends of the association between gut microbiota and neuroinflammation. [PDF]
Front MicrobiolWu S, Chen N, Wang C, So KF.
europepmc +1 more source
Animal Models for DOHaD Research: Focus on Hypertension of Developmental Origins. [PDF]
Biomedicines, 2021 Hsu CN, Tain YL.
europepmc +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Retraction notice to "A review on the energy in buildings: Current research focus and future development direction" [Heliyon 10 (2024) e32869]. [PDF]
HeliyonSu Y, Jin Q, Zhang S, He S.
europepmc +1 more source
Understanding Views Around the Creation of a Consented, Donated Databank of Clinical Free Text to Develop and Train Natural Language Processing Models for Research: Focus Group Interviews With Stakeholders. [PDF]
JMIR Med Inform, 2023 Fitzpatrick NK +6 more
europepmc +1 more source