Results 191 to 200 of about 82,140,510 (321)

Research Summaries in Focus

Smile Dental Journal, 2015
openaire   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

AxIOM: Amphipod crustaceans from insular Posidonia oceanica seagrass meadows

Biodiversity Data Journal, 2016
Loïc Michel, Nicolas Sturaro, André Heughebaert, Gilles Lepoint   +3 more
doaj   +3 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Future research focus and trends in nerve transplantation: a bibliometrics research from 2015 to 2024. [PDF]

Front Neurol
Wang S, Lu J, Han H, Li Y, Lu N, Chen A.
europepmc   +1 more source

Utilising Induced Pluripotent Stem Cells in Neurodegenerative Disease Research: Focus on Glia. [PDF]

Int J Mol Sci, 2021
Albert K, Niskanen J, Kälvälä S, Lehtonen Š.   +3 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The research focus and frontiers in surgical treatment of essential tremor. [PDF]

Front Neurol
Zhang L, Cui S, Bi H, Chen Q, Kan M, Wang C, Pu Y, Cheng H, Huang B.   +8 more
europepmc   +1 more source

Ocular Surface Ion-Channels Are Closely Related to Dry Eye: Key Research Focus on Innovative Drugs for Dry Eye. [PDF]

Front Med (Lausanne), 2022
Yang S, Wu Y, Wang C, Jin X.
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source