Results 101 to 110 of about 9,092,681 (307)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
History of research activities on guayule (Parthenium argentatum) at Cirad since the 1980s [PDF]
, 2019 Interest for guayule (Parthenium argentatum) in France started in the 1950s at the French Rubber institute (IFC), in parallel with research on Hevea Brasiliensis in Indochina.
Chapuset, Thierry +2 more
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Oral History as Inquiry: Using Digital Oral History Collections to Teach School Desegregation [PDF]
, 2018 A body of literature in both history and history education indicates that when it comes to contemporary historical issues, oral history is one of the essential sources to investigate the past, particularly as a source for “history from below ...
Daugherity, Brian J., Suh, Yonghee
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Music of Minorities—“The Others from Within”? On terminology and the history of research in Austria
Musicologica Austriaca, 2015 This article looks into the history of the disciplines folk music research and ethnomusicology (comparative musicology) using the Viennese case as a rather representative example for both disciplines. It includes a personal account as the author has been
Ursula Hemetek
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
History of mineralogical research
Fides et Ratio, 2018 Mineralogy is one of the oldest scientific disciplines, dynamically developing over the centuries. This article will present the history of this field.
Roksana Maćkowska
doaj