Results 81 to 90 of about 3,895,024 (310)

WS44: History of the Avon Longitudinal Study of Parents and Children (ALSPAC), c.1980-2000 (24-May-2011)

open access: yes, 2017
Selection of photos taken at the Witness Seminar “History of the Avon Longitudinal Study of Parents and Children (ALSPAC), c.1980-2000” held by the History of Modern Biomedicine Research Group, 24-May-2011.

core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

WS58: Air Pollution Research in Britain c.1955–c.2000 (19-May-2015)

open access: yes, 2017
Selection of photos taken at the Witness Seminar “Air Pollution Research in Britain c.1955–c.2000" held by the History of Modern Biomedicine Research Group, 19-May-2015. Participants: Professor H.

core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Genetic animal modeling for idiopathic scoliosis research: history and considerations. [PDF]

open access: yesSpine Deform, 2022
Terhune EA   +5 more
europepmc   +1 more source

WS42: History of British Intensive Care, c. 1950-c. 2000 (16-Jun-2010)

open access: yes, 2017
Selection of photos taken at the Witness Seminar “History of British Intensive Care, c. 1950-c. 2000” held by the History of Modern Biomedicine Research Group,16-Jun-2010.

core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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