Results 41 to 50 of about 106,644 (264)
Frontiers in OncologyObjectiveTo explore the current status of therapeutic drug monitoring (TDM) research on anticancer drugs, analyze research hotspots and trends, and provide insights and references for future studies.MethodsData were retrieved from the Web of Science Core
Can Qian +9 more
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地震科学进展, 2021 As a new discipline in the field of earth science，tectonic geomorphology has unique significance and scientific connotation of resources and environment.
Ziyue Shi +5 more
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Buildings, 2022 With the significant increase in global ageing and its derivative risks, governments and academic communities have been widely concerned with research on facilities of combined medical and nursing care for the elderly (FCMNCE).
Zhe Chen, Qiang Yao, Na An
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Research hotspots and trends of plumbagin: A bibliometric perspective
MedicinePlumbagin is a biologically active naphthoquinone compound. Research related to plumbagin has gained popularity, evidenced by a gradual increase in publications. However, a bibliometric study in this field has yet to be conducted. Consequently, this study aims to evaluate the global scientific output of plumbagin research through bibliometric analysis,
Zichen Xu +7 more
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Unveiling the complex networks of urban tree diversity research: A global perspective
Ecology and EvolutionEcosystem services offered by urban forests must be proactively managed to remain diverse and sustainable. Recent research findings deserve a systematic synthesis to elucidate inherent knowledge structures and dynamics.
Chunping Xie +3 more
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Bibliometric Analysis of the Research (2000–2020) on Land-Use Carbon Emissions Based on CiteSpace
Land, 2023 Carbon emissions are critical to climate change, and land-use change is an essential source of growth in carbon emissions. Research on land-use carbon emissions has become one of the hotspots in academic research.
Xiaoping Li +5 more
doaj +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Research Hotspots of Regional Resilience and the Visualization of Research Frontiers
Redai dili, 2021 As a hot regional research realm, regional resilience provides a new research perspective toward regional sustainable development. At the same time, regional resilience is also an important research paradigm of sustainability science. Based on literature from a core database (Web of Science) launched between 1991 and 2019 on the topic of "regional ...
Han Zenglin, Zhu Wenchao, Li Bo
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