Results 41 to 50 of about 121,781 (311)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

The Evolution, Hotspots, and Trends in Research on Facilities of Combined Medical and Nursing Care for the Elderly

open access: yesBuildings, 2022
With the significant increase in global ageing and its derivative risks, governments and academic communities have been widely concerned with research on facilities of combined medical and nursing care for the elderly (FCMNCE).
Zhe Chen, Qiang Yao, Na An
doaj   +1 more source

Research hotspots and trends of plumbagin: A bibliometric perspective

open access: yesMedicine
Plumbagin is a biologically active naphthoquinone compound. Research related to plumbagin has gained popularity, evidenced by a gradual increase in publications. However, a bibliometric study in this field has yet to be conducted. Consequently, this study aims to evaluate the global scientific output of plumbagin research through bibliometric analysis,
Zichen Xu   +7 more
openaire   +2 more sources

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Unveiling the complex networks of urban tree diversity research: A global perspective

open access: yesEcology and Evolution
Ecosystem services offered by urban forests must be proactively managed to remain diverse and sustainable. Recent research findings deserve a systematic synthesis to elucidate inherent knowledge structures and dynamics.
Chunping Xie   +3 more
doaj   +1 more source

Bibliometric Analysis of the Research (2000–2020) on Land-Use Carbon Emissions Based on CiteSpace

open access: yesLand, 2023
Carbon emissions are critical to climate change, and land-use change is an essential source of growth in carbon emissions. Research on land-use carbon emissions has become one of the hotspots in academic research.
Xiaoping Li   +5 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Research Hotspots of Regional Resilience and the Visualization of Research Frontiers

open access: yesRedai dili, 2021
As a hot regional research realm, regional resilience provides a new research perspective toward regional sustainable development. At the same time, regional resilience is also an important research paradigm of sustainability science. Based on literature from a core database (Web of Science) launched between 1991 and 2019 on the topic of "regional ...
Han Zenglin, Zhu Wenchao, Li Bo
openaire   +1 more source

Research hotspots and future trends of hot corrosion research: a bibliometric analysis

open access: yesRSC Advances, 2023
Knowledge map of hot corrosion research: six research hotspots of the hot corrosion research field were elucidated.
Andrieanto Nurrochman   +4 more
openaire   +2 more sources

Hotspot in UTP [PDF]

open access: yes, 2004
In today's world, it is necessary for organizations especially educational institution to keep up with the latest trend in technology. Technology changes practically everyday and it is important for these organizations to explore the world of ...
Karunagaran, Nishalini
core  

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