Results 121 to 130 of about 6,818,964 (313)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Swinburne's Research Impact magazine (Issue 1, March 2016)
Swinburne University of Technology
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Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Episode 1: An Introduction to Research for Social Impact
Welcome to the first episode of the Research for Social Impact podcast! In this episode, we wanted to take the opportunity to introduce you to the Centre for Social Impact (CSI) at Swinburne University of Technology, and provide an overview of our ...
Professor Erin Wilson +2 more
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Swinburne's Research Impact Magazine (Issue 3, March 2018)
Swinburne University of Technology
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Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Swinburne's Research Impact magazine (Issue 4, January 2019)
Swinburne University of Technology
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The Research Impact Strategy Playbook: Getting ready for the research impact revolution
This playbook is for the individual researcher, research leader or research strategist who wants to begin the process of introducing a research impact capability to themselves, their team, school, discipline or higher education institution (HEI) and ...
Newman, Victor, Phillips, Paul A.
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Swinburne's Research Impact magazine (Issue 2, March 2017)
Swinburne University of Technology
core

