Results 121 to 130 of about 11,395,926 (309)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Annual Report : July 1, 1988-June 30,1989 [PDF]

open access: yes, 1990
not peer reviewedSubmitted by Laura Barnes (l-barnes@illinois.edu) on 2013-10-03T18:45:41Z No. of bitstreams: 1 annualreportjul0illi.pdf: 6612531 bytes, checksum: 0eaab2777440225fdc08fe43025ed919 (MD5)Made available in DSpace on 2013-10-03T18:45:41Z (GMT)
Illinois. Hazardous Waste Research and Information Center
core  

A pesquisa na área de ciência da informação

open access: yesTransinformação
Análise da pesquisa em Ciência da Informação a partir da produção de 5 programas de pós-graduação do país.
Johanna W. Smit
doaj  

Predictive Analytics and the Return of "Research" Information to Participants. [PDF]

open access: yesAppl Hum Factors Ergon Conf, 2020
Wang S   +5 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Tracking down on 50-year History of Research about Information Management and Technology in Korea [PDF]

open access: yes, 2013
Dept. of Domestic Information Information Service Center Korea Institute of Science and Technology Information   +1 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Editorial : Archaeology and information research

open access: yes, 2019
The aim of this special issue is to highlight the interdisciplinary nexus in a series of papers that explore and investigate the intersections of archaeologies and the different areas of information research.
Huvila, Isto   +4 more
core  

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