Results 81 to 90 of about 873,999 (316)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Safe Streets, Safe Communities: Walking and Biking Infrastructure in Gulfton [PDF]

open access: yes, 2019
Efforts to improve street safety in the Houston region are tied to residents’ ability to access socioeconomic opportunities using different travel modes.
Walkin, Isabela   +5 more
core   +1 more source

OBIS Infrastructure, Lessons Learned, and Vision for the Future

open access: yesFrontiers in Marine Science, 2019
This mini-review paper analyses the achievements of the Ocean Biogeographic Information System (OBIS), as a distributed global data system and as a community of data contributors and users.
Eduardo Klein   +8 more
doaj   +1 more source

Information Infrastructure for Cooperative Research in Neuroscience

open access: yesComputational Intelligence and Neuroscience, 2009
The paper describes a framework for efficient sharing of knowledge between research groups, which have been working for several years without flaws. The obstacles in cooperation are connected primarily with the lack of platforms for effective exchange of experimental data, models, and algorithms.
Piotr J. Durka   +5 more
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Infrastructure and economic growth in Egypt [PDF]

open access: yes
In the past half a century, Egypt has experienced remarkable progress in the provision of infrastructure in all areas, including transportation, telecommunication, power generation, and water and sanitation.
Loayza, Norman V., Odawara, Rei
core  

Infrastructure, transport and productivity [PDF]

open access: yes, 2014
This information sheet reviews trends in Australian productivity with a focus on the transport sector. Well targeted investments in transport infrastructure result in productivity increases that benefit many other industries.

core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

International benchmarking of South Africa's infrastructure performance [PDF]

open access: yes
The paper provides a first systematic, comprehensive benchmarking of South Africa's infrastructure performance in four major sectors--electricity, water and sanitation, information and communication technology, and transportation--against the relevant ...
Bogetic, Zeljko, Fedderke, Johannes W.
core  

Home - About - Disclaimer - Privacy