Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Correction: A predictive and moderation model of depression in adolescents, and the creation of the Javier-Aliaga's single-item scales of happiness and self-efficacy (version 1.0). [PDF]
Javier-Aliaga D +3 more
europepmc +1 more source
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Development and psychometric evaluation of the Work-Family Enrichment Scale for married shift-working nurses in Korea: a methodological study. [PDF]
Park MJ, Kim IO.
europepmc +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Method Development for the Analysis of Carbonaceous Chondrites by Laser Desorption/Ionization and Secondary Ion Time-of-Flight Mass Spectrometry. [PDF]
Rados E, Frank J, Pittenauer E.
europepmc +1 more source
Large Language Models for Rapid Instrument Prototyping: Design and Structural Optimization of the Dry Eye Disease in Pregnancy Questionnaire (DED-PREG). [PDF]
Jaruchowska M +4 more
europepmc +1 more source
Development of a Brazilian Portuguese instrument to assess knowledge, attitudes, and practices of pregnant women with diabetes at a Brazilian center. [PDF]
Amorim CVA +7 more
europepmc +1 more source

