Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
A direct comparison of the measurement properties of the PROMIS-16 and EQ-5D-5L in the U.S. general population. [PDF]
Pham M, Craig BM, Peasgood T, Rencz F.
europepmc +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Measurement Instruments Used to Assess Caregiver Burden in Informal Caregivers of Adult Cancer Patients: A Systematic Review. [PDF]
Cerrone V +6 more
europepmc +1 more source
The integrated nurse self-leadership and caring scale: development and psychometric evaluation. [PDF]
Yuwanto MA +3 more
europepmc +1 more source
Development and Exploratory Validation of the Assisting Mealtime Scale for Dementia Care: Nursing Staff Perspectives on Mealtime Support. [PDF]
Tang HC +4 more
europepmc +1 more source
Minimally invasive versus conventional apical enlargement during retreatment of severely curved mesial canals: A micro-CT study. [PDF]
da Silva PJP +4 more
europepmc +1 more source
The PhenX Toolkit: Long COVID Collection of Standard Protocols. [PDF]
Krzyzanowski MC +10 more
europepmc +1 more source
Identifying older adults' communication support needs and preferences: a scoping review of measurement instruments. [PDF]
Manchha AV +11 more
europepmc +1 more source

