Results 61 to 70 of about 1,495,900 (311)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Computer Models for Musical Instrument Identification

open access: yes, 2006
PhDA particular aspect in the perception of sound is concerned with what is commonly termed as texture or timbre. From a perceptual perspective, timbre is what allows us to distinguish sounds that have similar pitch and loudness. Indeed most people are
Chetry, Nicolas D, Chetry, Nicolas D.
core  

Method for transmission error prediction and optimization of RV reducer based on ensemble learning

open access: yesAdvances in Mechanical Engineering
To address the coupled geometric and deformation errors in RV reducers, this study proposes a high-precision transmission error prediction method using Stacking ensemble learning, overcoming the limitations of rigid assumptions and inefficient finite ...
Youcheng Wang   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Instrument Choice in Environmental Policy [PDF]

open access: yes
We examine the extent to which various environmental policy instruments meet major evaluation criteria, including cost-effectiveness, distributional equity, minimization of risk in the presence of uncertainty, and political feasibility.
Parry, Ian W.H., Goulder, Lawrence H.
core  

Design and Research of New Syntactic Foam Pressure Parts

open access: yesMATEC Web of Conferences, 2017
With the development of materials and technology, new composite materials which can meet the requirement of new technology are produced, especially in some harsh conditions where traditional materials cannot meet the needs.
Fang Xiong   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Culture of attached and suspended Rhodopseudomonas faecalis in the presence of decomposing fish feed

open access: yesMicrobiologyOpen, 2019
An approach to culturing attached and suspended forms of Rhodopseudomonas faecalis by using compound fish feed with tap water in transparent containers is reported in this study.
Xiaodong Wang   +6 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Interfacing the Network: An Embedded Approach to Network Instrument Creation

open access: yes, 2012
This paper discusses the design, construction, and development of a multi-site collaborative instrument, The Loop, developed by the JacksOn4 collective during 2009-10 and formally presented in Oslo at the arts.on.wires and NIME conferences in 2011 ...
Tom Davis   +7 more
core  

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