Results 151 to 160 of about 21,392,268 (380)

Intellectual‐Integrity in Government‐Funded Research [PDF]

, 2020
Adam Heller
openalex   +1 more source

Connecting Response to Intervention and Grade Retention: Implications for School Leaders [PDF]

, 2018
Within all classrooms of public schools, teachers greet general education students acknowledging broad differences in their learning readiness and social skills (Fuchs, Fuchs, & Compton, 2010; Martin, 2010).
Range, Bret G., Yocom, Dorothy Jean
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Random Vibration Fatigue Life Analysis of Aeroengine Bolts Using the Frequency-Domain Method

Fatigue of Aircraft Structures
Bolt connections are widely used in aircraft engines due to their advantages of high stiffness, low weight, and ease of assembly and disassembly. However, they are subjected to complex stress states in service, including high preloads, combustion-induced
Tian Lilin, Wang Jun, Zhang Chaofeng, Guo Yuchao, Chang Liang   +4 more
doaj   +1 more source

Scientific integrity in research methods [PDF]

Frontiers in Psychology, 2015
Recent cases of research misconduct have prompted psychologists to suggest that there is too much vulnerability in the research process (e.g., Simmons et al., 2011; Pashler and Harris, 2012). Regardless of whether this is the case, ensuring the integrity of a discipline requires a clear understanding of what conventions and norms define the research ...
openaire   +3 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Education and training policies for research integrity: Insights from a focus group study [PDF]

, 2021
Krishma Labib, Natalie Evans, Rea Roje, Panagiotis Kavouras, Andrea Reyes Elizondo, Wolfgang Kaltenbrunner, Ivan Buljan, Tine Ravn, Guy Widdershoven, L.M. Bouter, Costas A. Charitidis, Mads P. Sørensen, Joeri K. Tijdink   +12 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Penulisan Bahasa Asing pada Iklan Harian Pekanbaru Mx [PDF]

, 2017
This research has a formulation problem, which is how foreign language is written based on integrity level in daily advertisement of Pekanbaru MX January 2017 edition?.
Charlina, C. (Charlina), Mustafa, M. N. (M), Sari, N. P. (Nengsih)   +2 more
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source