Results 271 to 280 of about 21,392,268 (380)

Seminar on Research Integrity for IPZ students at A'dam Univ Applied Sci

Gerben ter Riet
openalex   +1 more source

Artificial intelligence, generative artificial intelligence and research integrity: a hybrid systemic review [PDF]

Khalid Arar, Hamit Özen, Gülşah Polat, Selahattin Turan   +3 more
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Fostering Research Integrity through Training: The training materials of four EU-funded projects through the lens of pedagogical underpinnings and three taxonomies of learning. [PDF]

Open Res Eur
Löfström E, Lindemann T, Blom F, Evans N, van den Hoven M, Inguaggiato G, Kavouras P, Lanzerath D, Priess-Buchheit J, Santos R, Tammeleht A, Wall PJ, Zollitsch L.   +12 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Integrating survivors with frontline trauma providers: a winning strategy for providers, survivors, and research integrity. [PDF]

Trauma Surg Acute Care Open
Newcomb A, Ritter GS.
europepmc   +1 more source

High integrity software for nuclear power plants: Candidate guidelines, technical basis and research needs. Executive summary: Volume 1

, 1995
S. Seth, William G. Bail, D. Cleaves, Henri Cohen, Duane Hybertson, Catiane Kelly Schaefer, George Stark, A. Ta, Bradford T. Ulery   +8 more
openalex   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Cairo Consensus Statement on Research Integrity of Randomised Clinical Trials. [PDF]

Pak J Med Sci
Chien PF, Khan KS, Fawzy M, Khalaf Y, Cairo Consensus Group on Research Integrity.   +4 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source