Results 161 to 170 of about 26,805,984 (378)
Molecular Oncology, EarlyView.This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga +8 more
wiley +1 more source
Research note: proxy responses in health surveys: a methodological issue [PDF]
, 1984 Monica E. Briscoe
openalex +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Clinical research methodology process: what has changed with COVID-19? [PDF]
Eur Heart J Suppl, 2022 Tavazzi L.
europepmc +1 more source
Methodology for urban rail and construction technology research and development planning [PDF]
A series of transit system visits, organized by the American Public Transit Association (APTA), was conducted in which the system operators identified the most pressing development needs.
Dayman, B. +4 more
core +1 more source
Molecular Oncology, EarlyView.We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin +10 more
wiley +1 more source
Vignette Research Methodology: An Essential Tool for Quality Improvement Collaboratives. [PDF]
Healthcare (Basel), 2022 Payton KSE, Gould JB.
europepmc +1 more source
Models and their testing: considerations on the methodology of agricultural research
, 1965 Th. J. Ferrari
openalex +2 more sources
Identifying creative research accomplishments : methodology and results for nanotechnology and human genetics [PDF]
Motivated by concerns about the organizational and institutional conditions that foster research creativity in science, we focus on how creative research can be defined, operationalized, and empirically identified.
Heinze, Thomas +3 more
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