Results 131 to 140 of about 1,952,261 (305)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
To Engage Research Critically : A Review of Kerry Howell ’s The Philosophy of Methodology [PDF]
, 2013 The turn to philosophical grounding in qualitative research demands a depth of historical and conceptual knowledge that many trained in the social sciences may lack.
Larkin, Allyson
core +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Understanding rural change - demography as a key to the future [PDF]
The last decades have seen a rapidly growing interest in foresight methodology. Methods have been developed in corporate and governmental communication exercises often labelled technology foresight.
Amcoff, Jan, Westholm, Erik
core
Understanding Visual Inquiry: A Review of Researching the Visual (2nd ed.) [PDF]
, 2014 The growing popularity of visual research in social sciences along with the new possibilities offered by the developments in technology necessitate including visual inquiry in research methodology classes.
Parylo, Oksana
core +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Systematic ReviewsSoftware that employs screening prioritization through active learning (AL) has accelerated the screening process significantly by ranking an unordered set of records by their predicted relevance. However, failing to find a relevant paper might alter the
Fionn Byrne +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Can qualitative and quantitative methods serve complementary purposes for policy research? [PDF]
Qualitative and quantitative methods in social science research have long been separate spheres with little overlap. However, recent innovations have highlighted the complementarity of qualitative and quantitative approaches. The Accra Food and Nutrition
Maxwell, Daniel G.
core
L'entretien de recherche avec des journalistes Editorial [PDF]
, 2012 International audienceThis is true of our first issue on interviews, a methodology which cuts across the fields of human and social sciences. We invite you to read it and consider what this particular research approach yields from real people in ...
Demers, François +3 more
core +2 more sources