Results 191 to 200 of about 1,735,729 (314)

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

Exploring the Role and Functionality of Ingredients in Plant-Based Meat Analogue Burgers: A Comprehensive Review

open access: yesFoods
The development of plant-based meat analogues has become a significant challenge for the food industry in recent years due to the increasing demand for sustainable and healthier proteins in the context of a global protein transition.
Gil Vila-Clarà   +3 more
doaj   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

open access: yesFEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu   +6 more
wiley   +1 more source

Digital Scholarship: Applying Digital Tools to Undergraduate Student Research Papers, A Proposal for a Freshman Seminar. Part I: Definition of Student Research Methodology

open access: yes, 2014
There are many digital tools that can be used for research and presentation in nearly every college discipline, including the social sciences and humanities. These tools hold the promise to radically change both the process and products of research.
Kann, Charles W.
core  

Bone‐wise rigid registration of femur, tibia, and fibula for the tracking of temporal changes

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background Multiple myeloma (MM) induces temporal alterations in bone structure, such as osteolytic bone lesions, which are challenging to identify through manual image interpretation. The large variation in radiologists' assessments, even at expert centers, further complicates diagnosis.
Arttu Ruohola   +5 more
wiley   +1 more source

Impact of bulk density assignment of bone on MRI‐based abdominal region radiotherapy planning for MR‐linac workflow

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose The purpose of the present study was to evaluate the impact of bone relative electron density (rED) assignment on radiotherapy planning for the abdominal region. Methods Twenty patients who received abdominal radiotherapy using MR‐Linac and underwent magnetic resonance imaging (MRI) and computed tomography (CT) simulation were analyzed.
Kota Abe   +4 more
wiley   +1 more source

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