Results 31 to 40 of about 1,337,098 (143)
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Molecular Oncology, EarlyView.Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi +6 more
wiley +1 more source
Developing the egovernment research agenda [PDF]
, 2007 This paper presents an exploratory research project to determine the needs for future eGovernment research. The project aimed particularly at getting relevant stakeholder views as a contrast to the received academic wisdom or political rhetoric.
Elliman, T, Irani, Z, Jackson, P
core +1 more source
Use of measurement theory for operationalization and quantification of psychological constructs in systems dynamics modelling [PDF]
, 2016 The analytical tools available to social scientists have traditionally been adapted from tools originally designed for analysis of natural science phenomena.
Ara Yeghiazarian +12 more
core +1 more source
Molecular Oncology, EarlyView.This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke +12 more
wiley +1 more source
Does Germany Need a (New) Research Ethics for the Social Sciences? [PDF]
This paper evaluates the German, UK, and US approaches to dealing with research ethics in the social sciences. It focuses 1) on the extent to which these research ethic frameworks protect the key rights of research subjects and 2) the extent to to which ...
Claudia Oellers, Eva Wegner
core
A methodological approach to evaluate elderly-robot interactions [PDF]
, 2018 The relevance in the study of interaction between elderly and robots may depend on the choice of activities that robots can be developed to perform and the assessment of their impact and importance for older people.
Gonçalves, Paulo +4 more
core
Quantifying human subjectivity using Q method : when quality meets quantity [PDF]
, 2014 Incorporating human subjectivity in applied disciplines of social sciences and other base sciences poses a challenge as the nature of qualitative data is often the point of contention.
Grodzińska-Jurczak, Małgorzata +2 more
core +1 more source
Molecular Oncology, EarlyView.We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić +31 more
wiley +1 more source
Reading Foucault: Genealogy and Social Science Research Methodology and Ethics [PDF]
Foucault's work has given rise to an increased methodological sensitivity of the political dangers associated with traditional qualitative approaches in the social sciences.
Wendy Bastalich
core
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source