Results 211 to 220 of about 12,197,949 (364)

Statistical methods in research

The Lancet, 1993
E R, Greenberg, T A, Stukel, J A, Baron, D H, Freeman   +3 more
openaire   +2 more sources

Evaluation of a 'Research Methods' Training Course for Novice Lived Experience Researchers. [PDF]

Health Expect
Grundy AC, Bhutta A, Mahyoub A, Jenkins R, Mir S, Miah J, Faragher G, Lovell K.   +7 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

New institutionalism at the heuristic frames - historical roots, social theories, research methods [recenzja książki]: Chmielewski, Piotr. 2011. Homo agens : instytucjonalizm w naukach społecznych. Warszawa : Wydawnictwo Poltext [PDF]

, 2014
Katarzyna Leszczyńska
openalex   +1 more source

Historical psychology: The relevance of the method and the potential for scientific research (based on generalizing Russian research)

, 2021
Marina Yu. Lachaeva
openalex   +1 more source

Research on Text Representation Method Based on Improved TF-IDF [PDF]

, 2020
Yu Fu, You Yu
openalex   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Keynote: Visual Methods: Sociology and Beyond

, 2014
This talk was presented at the 6th ESRC Research Methods Festival in July ...
Harper, Douglas
core  

Radiomics in preclinical imaging research: methods, challenges and opportunities. [PDF]

Npj Imaging
Riberdy V, Guida A, Rioux J, Brewer K.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source