Results 301 to 310 of about 12,197,949 (364)

Assessing computational reproducibility in Behavior Research Methods. [PDF]

Behav Res Methods
Ellis DA, Towse J, Brown O, Cork A, Davidson BI, Devereux S, Hinds J, Ivory M, Nightingale S, Parry DA, Piwek L, Shaw H, Towse AS.   +12 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Social Media Marketing of Non-Evidence-Based Women's Health Interventions: Protocol for a Content Analysis Using Participatory Research Methods. [PDF]

JMIR Res Protoc
Nickel B, Copp T, Gram E, Hersch J, Hudson C, McFadden K, Pickles K, Smith J, Taba M, Graham A, Freeman B, Mintzes B, Doust J, Cohen D, McCaffery K.   +14 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Fundamentals of Quantitative Research Methods in Mental Health Nursing. [PDF]

J Psychiatr Ment Health Nurs
Slater P.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Machine learning research methods to predict postoperative pain and opioid use: a narrative review. [PDF]

Reg Anesth Pain Med
Langford DJ, Reichel JF, Zhong H, Basseri BH, Koch MP, Kolady R, Liu J, Sideris A, Dworkin RH, Poeran J, Wu CL.   +10 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Decolonization in sexual and reproductive health research methods: a scoping review. [PDF]

BMC Health Serv Res
Stevens-Uninsky M, Barkhad A, MacDonald T, Perez A, Mbuagbaw L.   +4 more
europepmc   +1 more source