Results 111 to 120 of about 2,176,109 (306)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The Implication of Cultural Revolution and Economic Reform on Rural Women’s Political Participation in Post-Mao China

open access: yes, 2019
Since the passage of the Organic Law of Village Committees in 1987, direct election of village leaders has been conducted in China, and eventually reached a national scale after ten years’ experiment.
Jiang, Ouwen
core  

Identifying ‘Immigrants’ through Violence: Memory, Press, and Archive in the making of ‘Bangladeshi Migrants’ in Assam [PDF]

open access: yes, 2018
This research studies the violent conflict between Bengali Muslims, who mostly migrated from the former East Bengal during colonial times, and the Bodo Tribe, who mostly follow the Bathou religion in the Bodoland region of Assam.
Iqbal, M., Iqbal, M.
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The social role of design representation [PDF]

open access: yes, 2009
Design representation is a crucial part of all design activity. Representations provide a vehicle through which design ideas and decisions are explored, communicated and recorded.
Carroll, Jennie, Keller, Susan
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Efeito das modalidades de resposta sobre a estruturação de uma representação social: o exemplo da representação dos estudos

open access: yesInteramerican Journal of Psychology, 2011
A research relating to the social representation of the studies was carried out in order to explore the potential effect of the answers modalities in a calling into question questionnaire.
Thémis Apostolidis   +3 more
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Review: Sarah Pink (2001). Doing Ethnography: Images, Media and Representation in Research

open access: yesForum: Qualitative Social Research, 2002
In Doing Ethnography: Images, Media and Representation in Research, Sarah PINK outlines the possibilities and practicalities of visual methods in ethnographic research.
Laurie Mullen
doaj  

Predictability of mobile phone associations [PDF]

open access: yes, 2010
Prediction and understanding of human behavior is of high importance in many modern applications and research areas ranging from context-aware services, wireless resource allocation to social sciences.
Hansen, Lars Kai   +4 more
core  

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