Results 101 to 110 of about 24,559,807 (339)
Frontiers in SociologyThe post-2008 economic recovery period has seen varying degrees of improvement in the well-being of young individuals across different countries, regions, and cities of the EU.
Márton Medgyesi +2 more
doaj +1 more source
NOVEL RESEARCH FUNDING OPPORTUNITIES
Artery Research, 2018 It is a fortunate paradox that research motivated simply by a wish to better understand the natural world can later result in the most powerful applications imaginable. By definition, the outcome of any research is unknown until the research is finished.
Warwick Anderson
doaj +1 more source
Research opportunities on the Space Station [PDF]
Two interdisciplinary facilities that have been proposed for the Space Station, the Gas-Grain Simulation Facility and the Cosmic Dust Collector Facility, are reviewed.
Fogleman, Guy
core +1 more source
Quality of life after liver transplantation : state of the art [PDF]
, 2016 Quality of life (QoL) after deceased donor liver transplantation is increasingly recognized as a major outcome parameter. We reviewed recent publications in this rapidly evolving field in order to summarize recent achievements in the field and to define ...
Berrevoet, Frederik +9 more
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
An adaptive feedback methodology for determining information content in stable population studies
Mathematical Biosciences and Engineering, 2016 We develop statistical and mathematical based methodologies for determining (as the experiment progresses) the amount of information required to complete the estimation of stable population parameters with pre-specified levels of confidence.
H. T. Banks +3 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Engaging youth in post-disaster research: Lessons learned from a creative methods approach [PDF]
, 2016 Children and youth often demonstrate resilience and capacity in the face of disasters. Yet, they are typically not given the opportunities to engage in youth-driven research and lack access to official channels through which to contribute their ...
Cox, Robin S +5 more
core +3 more sources