Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Ranking Brazilian research output [PDF]
Nature, 2013 Helena B. Nader, Jacob Palis
openaire +1 more source
The 2012 world health report 'no health without research': the endpoint needs to go beyond publication outputs. [PDF]
, 2012 Frenk +13 more
core +2 more sources
Aggregated Erevnametrics: bringing together alt-metrics through Research Objects
This position paper examines the spectrum of artefacts that contribute to the research process, in the context of bibliometrics and erevnametrics. We examine how existing research evaluation techniques could be enhanced with richer information about the ...
Carr, Les +4 more
core
Drivers of Academic Research and Patenting in India: Econometric Estimation of the Research Production Function [PDF]
In this paper we attempt to provide a comprehensive understanding of the drivers ofacademic research and patenting in India. Academic research is conceptualised as aresearch production process where research inputs (like research time and number ...
Amit Shovon Ray, Sabyasachi Saha
core
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Journal of Data and Information ScienceTo explore how different types of research funding affect research papers, with implications for optimizing funding policies and promoting sustainable research development.
Wang Jean J., Wei Shu, Ye Fred Y.
doaj +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Scientific Outputs of Brazilian Postgraduate Research Groups [PDF]
Paidéia (Ribeirão Preto)Sonia Maria Guedes Gondim +3 more
doaj +1 more source