Results 211 to 220 of about 362,854 (260)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

AI-assisted thematic synthesis of existing neurological core outcome sets: A descriptive reference framework (COS-Neuro). [PDF]

PLoS One
Tiong SP, Yang X, Touzet AY, Millward CP, Zipser CM, Tetreault L, Gharooni A, Davies BM.   +7 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Human-AI Interaction in Interventional Radiology: A Narrative Review of Current Applications, Challenges, and Future Directions. [PDF]

J Imaging
Mariotti F, Cacioppa LM, Rossini N, Bruno A, Francavilla G, Felicioli A, Macchini M, Coppola A, Cellina M, Floridi C.   +9 more
europepmc   +1 more source

Cropland mask dataset for the Canadian Prairies derived from Google satellite embedding imagery. [PDF]

Data Brief
Ha T, Nketia KA, Neudorf S, Shirtliffe SJ.   +3 more
europepmc   +1 more source

A formative evaluation of the TB Think Tank's role and influence on TB policy in South Africa. [PDF]

PLOS Glob Public Health
Schmidt BM, Mulopo C, Mayieka L.
europepmc   +1 more source

Participatory Digital Twins for Chronic Care: From Predictive Models to Shared Sensemaking. [PDF]

J Particip Med
Li Q, Xie B, Johnson E, Li J.
europepmc   +1 more source

Algorithmic Habituation: A Neurocognitive and Systems-Based Framework for Human-AI Co-Adaptation. [PDF]

Brain Sci
Mladin NC, Rad D, Coman DȘ, Popescu MG, Felea MI, Marcu R, Rad G.   +6 more
europepmc   +1 more source