Results 51 to 60 of about 1,666,160 (306)

Sending your research material into the future [PDF]

, 2012
A leaflet offering practical guidance for researchers on how to preserve their digital research material/data. This is one of the outputs of the JISC SHARD project, investigating research data preservation for history researchers, and related projects in
Collins, Anna, Raggett, Malcolm, Sleeman, Patricia   +2 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Libraries and the management of research data [PDF]

, 2010
A discussion of the role of university libraries in the management of digital research data outputs. Reviews some of the recent history of progress in this area from a UK perspective, with reference to international ...
Lewis, M.J.
core  

Fostering open science practice through recognising and rewarding research data management and curation skills [PDF]

, 2016
In a bid to improve research integrity, drive innovation, increase knowledge and to maximize public investment, researchers are increasingly under pressure to work in a more open and transparent way.
Davidson, Joy
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Bibliometric analysis of logistics and supply chain research (2020–2024)

International Business Logistics Journal
PurposesThis study presents a comprehensive bibliometric analysis of logistics and supply chain management (LSCM) research published between 2020 and 2024, addressing the central research question: What are the trends, key research themes, and leading ...
Mahmoud Khalifa
doaj   +1 more source

Research Outputs of England’s Hospital Episode Statistics (HES) Database: Bibliometric Analysis

Journal of Innovation in Health Informatics, 2017
Background: Hospital administrative data, such as those provided by the Hospital Episode Statistics (HES) database in England, are increasingly being used for research and quality improvement. To date, no study has tried to quantify and examine trends in
Zain Chaudhry, Fahmida Mannan, Angela Gibson-White, Usama Syed, Shirin Ahmed, Azeem Majeed   +5 more
doaj   +1 more source

Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence

Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari, Caterina Costagliola, Marta Nebiolo, Francesca Parisi, Martina Morini, Katia Mazzocco, Gabriele Gaggero, Stefano Volpi, Stefania Sorrentino, Virginia Livellara   +9 more
wiley   +1 more source