Results 61 to 70 of about 1,666,160 (306)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Repository profile: University of Glasgow: "Enlighten" IR & Research System [PDF]
, 2014 The University of Glasgow has established the “Enlighten” IR and Research system. The IR holds 72,000 items for institutional peer-reviewed journal articles, published conference papers, books and book chapters.<p></p> The Research System ...
de Castro, Pablo +2 more
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Drug repurposing in cancer research: a bibliometric analysis
Discover OncologyCancer is one of the most pressing global health challenges. Drug repurposing is regarded as the most effective strategy in developing drug candidates by using therapeutic characteristics of well-known drugs. A bibliometric analysis was conducted on drug
Uche Samuel Ndidi +3 more
doaj +1 more source
Improving Research Output and Visibility through Open Access Research Discovery Solution- Dimensions at Obafemi Awolowo University [PDF]
, 2022 Joy Owango
openalex +1 more source
Peer assessment of research: how many publications per staff? [PDF]
, 2009 The UK's higher education funding councils have proposed reducing the number of submitted outputs from four to three in the forthcoming Research Excellence Framework to reduce the burden on panel members. This reduction is considered to be sufficient for
Taylor, J, Walker, I
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
UK Research Funders’ Policies for the Management of Information Outputs
International Journal of Digital Curation, 2008 A successful research and innovation system depends on the open exchange of ideas, information and knowledge. But both research methods and the scholarly communications system are undergoing fundamental changes which present new opportunities and ...
Michael Jubb
doaj +6 more sources