Results 71 to 80 of about 1,650,608 (285)

Bibliometric analysis of logistics and supply chain research (2020–2024)

open access: yesInternational Business Logistics Journal
PurposesThis study presents a comprehensive bibliometric analysis of logistics and supply chain management (LSCM) research published between 2020 and 2024, addressing the central research question: What are the trends, key research themes, and leading ...
Mahmoud Khalifa
doaj   +1 more source

Research Output Repositories

open access: yes, 2017
•What is a repository system? •How to compare repository systems? •What systems are out there? •What can we learn from Portugal? •(How to introduce a repository system?) This presentation is NOT about recommending you a specific ...
openaire   +1 more source

Repository profile: University of Glasgow: "Enlighten" IR & Research System [PDF]

open access: yes, 2014
The University of Glasgow has established the “Enlighten” IR and Research system. The IR holds 72,000 items for institutional peer-reviewed journal articles, published conference papers, books and book chapters.<p></p> The Research System ...
de Castro, Pablo   +2 more
core  

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

A methodological approach for algorithmic composition systems' parameter spaces aesthetic exploration [PDF]

open access: yes, 2017
Algorithmic composition is the process of creating musical material by means of formal methods. As a consequence of its design, algorithmic composition systems are (explicitly or implicitly) described in terms of parameters.
Múgica Álvarez, Francisco   +4 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Drug repurposing in cancer research: a bibliometric analysis

open access: yesDiscover Oncology
Cancer is one of the most pressing global health challenges. Drug repurposing is regarded as the most effective strategy in developing drug candidates by using therapeutic characteristics of well-known drugs. A bibliometric analysis was conducted on drug
Uche Samuel Ndidi   +3 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

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