Results 161 to 170 of about 5,285,257 (310)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Can the Child Behavior Checklist (CBCL) help characterize the types of psychopathologic conditions driving child psychiatry referrals? [PDF]

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, 2020
Joseph Biederman, Maura DiSalvo, Carrie Vaudreuil, Janet Wozniak, Mai Uchida, K. Yvonne Woodworth, Allison Green, Stephen V. Faraone   +7 more
doaj   +1 more source

Beyond Indicators and Success Stories: An Emerging Method to Assess Social Learning in Large-Scale Transdisciplinary Research Programs. [PDF]

Front Sociol, 2021
Huang YS, Harvey B.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Research programs

The Bible of AI ™ OpenScience, 2020
openaire   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Hands-on summer research programs at Indiana university Simon comprehensive cancer center. [PDF]

Discov Educ
Yeh ES, Hawkins SM, Byram J, Jengelley DHA, Buck GA, Scribner JA, Nakshatri H.   +6 more
europepmc   +1 more source

Ion beam applications research. A summary of Lewis Research Center Programs [PDF]

A summary of the ion beam applications research (IBAR) program organized to enable the development of materials, products, and processes through the nonpropulsive application of ion thruster technology is given. Specific application efforts utilizing ion
Banks, B. A.
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

GENERATIVE AI IN LEARNING DESIGN PRACTICE: BUILDING AN ONLINE COURSE FOR BIOMEDICAL SCIENCES RESEARCH PROGRAMS. [PDF]

Int J Des Learn
Suresh D, Dilek M, Karabulut-Ilgu A, Baran E, Kimber M.   +4 more
europepmc   +1 more source