Results 141 to 150 of about 1,965,480 (316)
Inhibiting cholesterol synthesis halts rhabdomyosarcoma growth via ER stress and cell cycle arrest
EMBO Molecular MedicineRhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma, with poor outcomes in high-risk and relapsed patients. Here, we identify de novo cholesterol biosynthesis as a critical metabolic vulnerability in RMS.
Nebeyu Yosef Gizaw +4 more
doaj +1 more source
The Nexus of HIV, substance abuse, and mental health among adolescents in Zambia (2021–2023)
Journal of Public Health in AfricaBackground: Adolescents in Zambia face interrelated health challenges, including human immunodeficiency virus (HIV), substance abuse and mental health disorders (MHDs). These issues have significant public health implications, as substance abuse and MHDs
Belia Longwe +10 more
doaj +1 more source
Integrating ayurvedic medicine into cancer research programs part 2: Ayurvedic herbs and research opportunities. [PDF]
J Ayurveda Integr Med, 2023 Arnold JT.
europepmc +1 more source
Research Naval Postgraduate School, v.11, no. 2, June 2001 [PDF]
, 2001 NPS Research is published by the Research and Sponsored Programs, Office of the Vice President and Dean of Research, in accordance with NAVSOP-35. Views and opinions expressed are not necessarily those of the Department of the Navy.Approved for public ...
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Research Programs in Japan [PDF]
Japanese Journal of Clinical Oncology, 1998 openaire +2 more sources
Research Naval Postgraduate School, v. 2, no. 8, May 2010 [PDF]
, 2010 NPS Research is published by the Research and Sponsored Programs, Office of the Vice President and Dean of Research, in accordance with NAVSOP-35. Views and opinions expressed are not necessarily those of the Department of the Navy.Approved for public ...
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Research Naval Postgraduate School, v.4, no. 9, May 2012 [PDF]
, 2012 NPS Research is published by the Research and Sponsored Programs, Office of the Vice President and Dean of Research, in accordance with NAVSOP-35. Views and opinions expressed are not necessarily those of the Department of the Navy.Approved for public ...
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source