Results 161 to 170 of about 77,403,001 (321)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Research Naval Postgraduate School, v.4, no. 14, October 2012 [PDF]

, 2012
NPS Research is published by the Research and Sponsored Programs, Office of the Vice President and Dean of Research, in accordance with NAVSOP-35. Views and opinions expressed are not necessarily those of the Department of the Navy.Approved for public ...

core  

Commentary: The poverty of embodied cognition

Frontiers in Psychology, 2017
Kinga Wołoszyn, Mateusz Hohol, Mateusz Hohol   +2 more
doaj   +1 more source

Enhancing Primary Care Capacity for Cardiovascular Disease Management Through the ECHO+ Model: A Multistate Rural Collaboration Among West Virginia, Arkansas, and Oklahoma

Journal of Primary Care & Community Health
Background: Cardiovascular diseases (CVD) are the leading cause of mortality in Arkansas, West Virginia, and Oklahoma, underscoring the need for approaches to build primary care capacity to address CVD in these states.
Dru Ricci, Hannah Schmitt, Heidi Ngov, Tessa Collins, Amie Pollack, Kirsten Meisinger, Anne-Marie Anagnostopoulos, Adam Vascellaro, Brody Eaton, Janie Knotts, David Duong   +10 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Research Naval Postgraduate School, v. 4, no. 13, September 2012 [PDF]

, 2012
NPS Research is published by the Research and Sponsored Programs, Office of the Vice President and Dean of Research, in accordance with NAVSOP-35. Views and opinions expressed are not necessarily those of the Department of the Navy.Approved for public ...

core  

Innovation in Large-Scale Research Programs: Elevating Research Participants to Governance Roles Through the All of Us Research Program Engagement Core. [PDF]

Acad Med, 2022
Fair A, Watson KS, Cohn EG, Carpenter SM, Richardson-Heron D, Wilkins CH.   +5 more
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Building Scientific Capability and Reducing Biological Threats: The Effect of Three Cooperative Bio-Research Programs in Kazakhstan. [PDF]

Front Public Health, 2021
Yeh KB, Tabynov K, Parekh FK, Maltseva E, Skiba Y, Shapiyeva Z, Sansyzbai A, Frey S, Essbauer S, Hewson R, Richards AL, Hay J.   +11 more
europepmc   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source