Results 191 to 200 of about 1,965,480 (316)

Editorial: The cognitive basis for decision making under risk and uncertainty: research programs & controversies. [PDF]

Front Psychol
Shye S, Viale R.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Documenting adaptations across the Accelerating Colorectal Cancer Screening and follow-up through Implementation Science research programs: methods and adaptation examples. [PDF]

Front Health Serv
Rabin BA, Kenzie ES, Oliveri JM, Kruse-Diehr AJ, Hoover S, Menon U, Doescher MP, Adsul P, Mishra SI, English K, Nodora J, Lam H, Kim K, Coury JK, Davis MM, Malo T, Kobrin S, Subramanian S, Ferrari RM.   +18 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

A trainee-informed model for undergraduate neuroscience research programs serving marginalized students. [PDF]

Nat Neurosci
Cazares C, Patiño M, Contreras M, Gorman JC, Burgado J, Ali SA, van Engen Q, Kosik EL, Riviere P, Baltz ET, Agba CK, Preston M, Nagarajan A, Cressy J, Paredes N, Santiago C, White KL.   +16 more
europepmc   +1 more source

Biomedical Research Programs at Present and Future High-Energy Particle Accelerators. [PDF]

Front Phys, 2020
Patera V, Prezado Y, Azaiez F, Battistoni G, Bettoni D, Brandenburg S, Bugay A, Cuttone G, Dauvergne D, de France G, Graeff C, Haberer T, Inaniwa T, Incerti S, Nasonova E, Navin A, Pullia M, Rossi S, Vandevoorde C, Durante M.   +19 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

A review of undergraduate research programs aimed at underrepresented students. [PDF]

STAR Protoc
Beasley HK, Vue Z, McReynolds MR, Neikirk K, Garza-Lopez E, Mungai M, Marshall AG, Shao B, Benjamin J, Wanjalla CN, Williams CR, Murray SA, Shuler HD, Kirabo A, Hinton A.   +14 more
europepmc   +1 more source

Promoting resilience of large international collaborative research programs in times of global crisis. [PDF]

Ecol Evol, 2020
Trogisch S, Albert G, Du J, Wang Y, Xue K, Bruelheide H.   +5 more
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source