Results 41 to 50 of about 1,362,093 (249)

Reaching hard-to-reach men through home-based couple HIV testing among pregnant women and their male partners in western Kenya: a qualitative study

open access: yesBMC Public Health, 2020
Background Globally only 79% of adults living with HIV (human immunodeficiency virus) know their status and men in sub-Saharan Africa are considered a particularly hard-to-reach population for HIV testing.
Daisy Krakowiak   +8 more
doaj   +1 more source

Psychological Safety Among Interprofessional Pediatric Oncology Teams in Germany: A Nationwide Survey

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Psychological safety (PS) is essential for teamwork, communication, and patient safety in complex healthcare environments. In pediatric oncology, interprofessional collaboration occurs under high emotional and organizational demands. Low PS may increase stress, burnout, and adverse events.
Alexandros Rahn   +4 more
wiley   +1 more source

Loss of mtDNA activates astrocytes and leads to spongiotic encephalopathy

open access: yesNature Communications, 2018
Astrocytes in the brain are metabolically dynamic. Here, Ignatenko, Chilov and colleagues delete mitochondrial DNA (mtDNA) in a cell type specific manner, and show that inactivation of mtDNA helicase Twinkle in astrocytes leads to spongiotic ...
Olesia Ignatenko   +9 more
doaj   +1 more source

Developmental Disorders in Children Recently Diagnosed With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag   +5 more
wiley   +1 more source

Editorial: Why should I?

open access: yesSustainability: Science, Practice, & Policy, 2007
Furthermore, I believe that given their head start in being necessarily embedded in complementary studies that cross disciplines, sustainability scientists can, by example, enhance the relevance of their work to that of other disciplines.
Sidney Draggan
doaj  

Metabolomes of mitochondrial diseases and inclusion body myositis patients: treatment targets and biomarkers

open access: yesEMBO Molecular Medicine, 2018
Mitochondrial disorders (MDs) are inherited multi‐organ diseases with variable phenotypes. Inclusion body myositis (IBM), a sporadic inflammatory muscle disease, also shows mitochondrial dysfunction.
Jana Buzkova   +11 more
doaj   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker   +7 more
wiley   +1 more source

Endothelial Pim3 kinase protects the vascular barrier during lung metastasis

open access: yesNature Communications
Endothelial cells (ECs) form a tissue-specific barrier for disseminating cancer cells in distant organs. However, the molecular regulation of the ECs in the metastatic niche remains unclear.
Niina M. Santio   +9 more
doaj   +1 more source

SALSA: a regulator of the early steps of complement activation on mucosal surfaces

open access: yesFrontiers in Immunology, 2016
Complement is present mainly in blood. However, following mechanical damage or inflammation, serous exudates enter the mucosal surfaces. Here the complement proteins interact with other endogenous molecules to keep microbes from entering the parenteral ...
Martin eReichhardt, Seppo eMeri
doaj   +1 more source

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li   +9 more
wiley   +1 more source

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